CNTN2 Protein (His tag)

N° du produit ABIN7318334

Détail du produit

Antigène: CNTN2 (Contactin 2 (Axonal) (CNTN2))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CNTN2 protéine est marqué à la His tag.

Fonction: Recombinant Human Contactin 2/CNTN2 Protein (His Tag)

Séquence: Ser31-Asn1012

Attributs du produit: Recombinant Human Transient axonal glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Asn1012 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CNTN2 (Contactin 2 (Axonal) (CNTN2))

Autre désignation: Contactin 2/CNTN2 (CNTN2 Produits)

Synonymes: tag1 Protein, si:dz37k09.2 Protein, CNTN2 Protein, D130012K04Rik Protein, TAG-1 Protein, Tax Protein, AXT Protein, TAX Protein, TAX1 Protein, AXONIN-1 Protein, TAG-564 Protein, TAG1 Protein, contactin 2 Protein, contactin 2 (axonal) Protein, cntn2 Protein, CNTN2 Protein, Cntn2 Protein

Sujet:

Background: Contactin-2 (CNTN2) is encoded by the CNTN2 gene,which belongs to the immunoglobulin superfamily and contactin family. It contains 4 fibronectin type-III domains and 6 Ig-like C2-type domains. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. CNTN2 may play a role in the formation of axon connections in the developing nervous system. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.

Synonym: Contactin-2, Axonal glycoprotein TAG-1, Axonin-1, Transient axonal glycoprotein 1, CNTN2, AXT, TAG1, TAX1

Poids moléculaire: 108.7 kDa

UniProt: Q02246

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size