CKB Protein (His tag)

N° du produit ABIN7319644

Détail du produit

Antigène: CKB (Creatine Kinase, Brain (CKB))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CKB protéine est marqué à la His tag.

Fonction: Recombinant Human Creatine Kinase BB/CKB Protein (His Tag)

Séquence: Met1-Lys381

Attributs du produit: Recombinant Human Creatine Kinase BB is produced by our E.coli expression system and the target gene encoding Met1-Lys381 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: CKB (Creatine Kinase, Brain (CKB))

Autre désignation: Creatine Kinase BB/CKB (CKB Produits)

Synonymes: B-CK Protein, CKBB Protein, b-ck Protein, ckbb Protein, CKB Protein, Bck Protein, Ck-3 Protein, Ck3 Protein, Ckbb Protein, bck Protein, ckb Protein, cb594 Protein, wu:fj36f10 Protein, wu:fj37d11 Protein, Ckbr Protein, mg:cb02h12 Protein, wu:fb62d04 Protein, wu:fc14g11 Protein, zgc:154095 Protein, zgc:92079 Protein, creatine kinase B Protein, creatine kinase, brain L homeolog Protein, creatine kinase B-type Protein, creatine kinase, brain Protein, creatine kinase, brain b Protein, creatine kinase, brain a Protein, CKB Protein, ckb.L Protein, Ckb Protein, ckb Protein, ckbb Protein, ckba Protein

Sujet:

Background: Creatine kinase B-type (CKB) belongs to the ATP:guanido phosphotransferase family. It has dimer of identical or non-identical chains with MM being the major form in skeletal muscle and myocardium. MB exists in myocardium, and BB exists in many tissues, especially brain. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Clinically, creatine kinase is assayed in blood tests as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, autoimmune myositides and acute renal failure.

Synonym: B-CK, CKB, Creatine Kinase BB

Poids moléculaire: 44.8 kDa

UniProt: P12277