EGR1 Protein (His tag)

N° du produit ABIN7318419

Détail du produit

Antigène: EGR1 (Early Growth Response 1 (EGR1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette EGR1 protéine est marqué à la His tag.

Fonction: Recombinant Human EGR1 Protein (His Tag)

Séquence: Gln282-Ser433

Attributs du produit: Recombinant Human Early growth response protein 1 is produced by our E.coli expression system and the target gene encoding Gln282-Ser433 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: EGR1 (Early Growth Response 1 (EGR1))

Autre désignation: EGR1 (EGR1 Produits)

Synonymes: AT225 Protein, G0S30 Protein, KROX-24 Protein, NGFI-A Protein, TIS8 Protein, ZIF-268 Protein, ZNF225 Protein, A530045N19Rik Protein, ETR103 Protein, Egr-1 Protein, Krox-1 Protein, Krox-24 Protein, Krox24 Protein, NGF1-A Protein, NGFIA Protein, Zenk Protein, Zfp-6 Protein, Zif268 Protein, egr Protein, Ngf1 Protein, Ngfi Protein, zif-268 Protein, EGR1 Protein, EGR-1-A Protein, Xegr-1 Protein, at225 Protein, egr-1 Protein, egr1 Protein, g0s30 Protein, krox-24 Protein, ngfi-a Protein, tis8 Protein, znf225 Protein, krox24 Protein, wu:fj64b05 Protein, wu:fq25f01 Protein, EGR-1 Protein, zenk Protein, EGR-1-B Protein, egr1-a Protein, egr1-b Protein, early growth response 1 Protein, early growth response protein 1 (egr-1) Protein, early growth response 1 L homeolog Protein, early growth response 1 S homeolog Protein, EGR1 Protein, CNK00890 Protein, Egr1 Protein, egr1.L Protein, egr1 Protein, egr1.S Protein

Sujet:

Background: EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).

Synonym: EGR-1, Early growth response protein 1, Zif268, zinc finger protein 225, NGFI-A , nerve growth factor-induced protein A,

Poids moléculaire: 19.9 kDa

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity