ESR2 Protein (His tag)

N° du produit ABIN7318452

Détail du produit

Antigène: ESR2 (Estrogen Receptor 2 (ESR2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ESR2 protéine est marqué à la His tag.

Fonction: Recombinant Human Estrogen Receptor β/ER beta Protein (His Tag)

Séquence: Met 1-Ala323

Attributs du produit: Recombinant Human Estrogen Receptor Beta is produced by our E.coli expression system and the target gene encoding Met1-Ala323 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM TrisHCl, pH 8.0.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ESR2 (Estrogen Receptor 2 (ESR2))

Autre désignation: Estrogen Receptor beta/ER beta (ESR2 Produits)

Synonymes: ER-BETA Protein, ESR-BETA Protein, ESRB Protein, ESTRB Protein, Erb Protein, NR3A2 Protein, ER[b]1 Protein, zfER-beta1 Protein, zfER[b]1 Protein, erb2 Protein, CERB Protein, ERB Protein, erb Protein, esrb Protein, estrb Protein, nr3a2 Protein, ERbeta Protein, er-beta Protein, esr-beta Protein, ESR2 Protein, ERBETA Protein, er Protein, ER-beta Protein, ER[b] Protein, Estrb Protein, ER[b]2 Protein, ER[b]a Protein, zfER[b]2 Protein, zfER-beta2 Protein, Erb2 Protein, esr2 Protein, erbeta Protein, Esr2 Protein, ERBeta2 Protein, estrogen receptor 2 Protein, estrogen receptor 2b Protein, estrogen receptor beta 2 Protein, estrogen receptor 2 (beta) Protein, estrogen receptor 2a Protein, estrogen receptor beta Protein, ESR2 Protein, esr2b Protein, erb2 Protein, esr2 Protein, Esr2 Protein, esr2a Protein, erbeta Protein

Sujet:

Background: Estrogen Receptor Beta (ESR2) is a nuclear protein that belongs to the nuclear hormone receptor family of NR3 subfamily. It contains one nuclear receptor DNA-binding domain and is expressed in many tissues at a lower level. ESR2 is a nuclear hormone receptor. It binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

Synonym: Estrogen Receptor Beta, ER-Beta, Nuclear Receptor Subfamily 3 Group A Member 2, ESR2, ESTRB, NR3A2

Poids moléculaire: 38.1 kDa

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling