FKBP7 Protein (Fc Tag)

N° du produit ABIN7317273

Détail du produit

Antigène: FKBP7 (FK506 Binding Protein 7 (FKBP7))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FKBP7 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human PPIase/FKBP7 Protein (Fc Tag)

Séquence: Met 1-Gln218

Attributs du produit: A DNA sequence encoding the human FKBP7 (Q9Y680-2) (Met1-Gln218) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: FKBP7 (FK506 Binding Protein 7 (FKBP7))

Autre désignation: PPIase/FKBP7 (FKBP7 Produits)

Synonymes: FKBP Protein, si:dz167c3.2 Protein, FKBP-7 Protein, DKFZp469I2124 Protein, FKBP23 Protein, PPIase Protein, 23kDa Protein, FK506 binding protein 7 Protein, FK506 binding protein 7 L homeolog Protein, fkbp7 Protein, FKBP7 Protein, fkbp7.L Protein, Fkbp7 Protein

Sujet:

Background: PPIase is a member of the immunophilin protein family. It also belongs to the cyclophilin-type PPIase family, PPIL3 subfamily. PPIase contains 1 PPIase cyclophilin-type domain. Members of the immunophilin protein family play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It has a very high substrate specificity for the four-residue peptide Ala-Ala-Pro-Phe only when the proline peptide bond is in the trans state. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Synonym: Peptidyl-Prolyl Cis-Trans Isomerase FKBP7, PPIase FKBP7, 23 kDa FK506-Binding Protein, 23 kDa FKBP, FKBP-23, FK506-Binding Protein 7, FKBP-7, Rotamase, FKBP7, FKBP23

Poids moléculaire: 49.4 kDa

Pathways: SARS-CoV-2 Protein Interactome