FZD2 Protein (Fc Tag)

N° du produit ABIN7320533

Détail du produit

Antigène: FZD2 (Frizzled Family Receptor 2 (FZD2))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette FZD2 protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse Frizzled 2/FZD2 Protein (Fc Tag)

Séquence: Gln29-Leu168

Attributs du produit: Recombinant Mouse frizzled (Drosophila) homolog 2 is produced by our Mammalian expression system and the target gene encoding Gln29-Leu168 is expressed with a Fc tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: FZD2 (Frizzled Family Receptor 2 (FZD2))

Autre désignation: Frizzled 2/FZD2 (FZD2 Produits)

Synonymes: BG01711 Protein, CG9739 Protein, D-Fz2 Protein, D-fz2 Protein, DFZ2 Protein, DFz-2 Protein, DFz2 Protein, Dfrz2 Protein, Dfz2 Protein, Dfz[[2]] Protein, Dm Fz2 Protein, Dmel\\CG9739 Protein, FZ2 Protein, Fz2 Protein, dFz2 Protein, dfz(2) Protein, dfz2 Protein, dfz2r Protein, frz2 Protein, fz-2 Protein, fz8 Protein, zfz2 Protein, zg08 Protein, cb383 Protein, wu:fb70g09 Protein, FZD2 Protein, fzE2 Protein, hFz2 Protein, Fz-10 Protein, Fzd10 Protein, cFz-2 Protein, frizzled2 Protein, fz2 Protein, xfz2 Protein, AL033370 Protein, AW456835 Protein, Fz10 Protein, Mfz10 Protein, Mfz10a Protein, frizzled 2 Protein, frizzled class receptor 2 Protein, frizzled class receptor 2 S homeolog Protein, fz2 Protein, fzd2 Protein, FZD2 Protein, Fzd2 Protein, fzd2.S Protein

Sujet:

Background: Wnt signaling plays a critical role in embryonic development, and genetic aberrations. Frizzled2 (Fzd2) is a receptor for wingless-type MMTV integration site family members (Wnts), the aberrant overexpression of which has been noted to contribute to cancer metastasis. Frizzled2 (Fzd2) and its ligands Wnt5a/b are elevated in metastatic liver, lung, colon, and breast cancer cell lines and in high-grade tumors and that their expression correlates with markers of epithelial-mesenchymal transition (EMT). It is also shown that Frizzled-2 expression is greater in embryonic than adult tissues, with heart, brain, lung, kidney and gut showing the highest levels.

Synonym: Frizzled-2, Fz-2, mFz2, Fzd2,frizzled (Drosophila) homolog 2

Poids moléculaire: 42.9 kDa

UniProt: Q9JIP6

Pathways: Signalisation WNT