FUT8 Protein (AA 68-575) (His tag)

N° du produit ABIN7317577

Détail du produit

Antigène: FUT8 (Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 68-575

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette FUT8 protéine est marqué à la His tag.

Fonction: Recombinant Human FUT8 Protein (aa 68-575, His Tag)(Active)

Séquence: Arg 68-Lys 575

Attributs du produit: A DNA sequence encoding the human FUT8 isoform 1 (Q9BYC5-1) (Arg 68-Lys 575) was fused with a polyhistidine tag at the carboxy-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to hydrolyze the donor substrate GDP fucose.The specific activity is >0.75 pmoles/min/μg.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: FUT8 (Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8))

Autre désignation: FUT8 (FUT8 Produits)

Synonymes: fucosyltransferase 8 Protein, FUT8 Protein, Fut8 Protein

Sujet:

Background: Alpha (1,6) fucosyltransferase 8, also known as FUT8, is a member of the glycosyltransferase family. Fucosyltransferases are the enzymes transferring fucose from GDP-Fuc to Gal in an alpha1,2-linkage and to GlcNAc in alpha1,3-linkage, alpha1,4-linkage, or alpha1,6-linkage. All fucosyltransferases utilize the same nucleotide sugar, their specificity reside in the recognition of the acceptor and in the type of linkage formed. Fucosyltransferases share some common structural and catalytic features. On the basis of protein sequence similarities, these enzymes can be classified into four distinct families: (1) the alpha-2-fucosyltransferases, (2) the alpha-3-fucosyltransferases, (3) the mammalian alpha-6-fucosyltransferases, and (4) the bacterial alpha-6-fucosyltransferases. The alpha-3-fucosyltransferases constitute a distinct family as they lack the consensus peptide, but some regions display similarities with the alpha-2 and alpha-6-fucosyltranferases.

Synonym: MGC26465

Poids moléculaire: 60 kDa