GPR37 Protein (His tag)

N° du produit ABIN7317239

Détail du produit

Antigène: GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GPR37 protéine est marqué à la His tag.

Fonction: Recombinant Human GPR37 Protein (His Tag)

Séquence: Met 1-Met 265

Attributs du produit: A DNA sequence encoding the human GPR37 (NP_005293.1) the first extracellular domaqin (Met 1-Met 265) was fused with a polyhistidine tag at the C-terminus.

Pureté: > 80 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))

Autre désignation: GPR37 (GPR37 Produits)

Synonymes: ACCA Protein, EDNRBL Protein, PAELR Protein, hET(B)R-LP Protein, AI848630 Protein, Pael-R Protein, Ednrbl Protein, G protein-coupled receptor 3 Protein, G protein-coupled receptor 37 Protein, GPR3 Protein, GPR37 Protein, Gpr37 Protein

Sujet:

Background: GPR37 (cathepsin Z) is an orphan receptor which belongs to the G-protein coupled receptor 1 family. G protein coupled receptors is a large protein family comprised by transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. They only exists in eukaryotes, including yeast, choanoflagellates, and animals. These receptors are binded and activated by light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters. These ligands vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases, and are also the target of approximately 40 % of all modern medicinal drugs. GPR37 is expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. GPR37 may have a unique functional role in the central nervous system.

Synonym: EDNRBL,hET(B)R-LP,PAELR

Poids moléculaire: 26.6 kDa

NCBI Accession: NP_005293