GBA3 Protein (His tag)

N° du produit ABIN7195930

Détail du produit

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette GBA3 protéine est marqué à la His tag.

Fonction: Recombinant Human GBA3/CBGL1 Protein (His Tag)(Active)

Séquence: Met 1-Leu 469

Attributs du produit: A DNA sequence encoding the human GBA3 (NP_066024.1) (Met 1-Leu 469) was fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to hydrolyze 4-methylumbelliferyl-β-D glucopyranoside. The specific activity is >1,500 pmoles/min/μg.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Autre désignation: GBA3/CBGL1 (GBA3 Produits)

Synonymes: im:6912508 Protein, CBG Protein, CBGL1 Protein, GLUC Protein, KLRP Protein, glucosylceramidase beta 3 Protein, glucosidase, beta, acid 3 (gene/pseudogene) Protein, glucosidase, beta, acid 3 (cytosolic) Protein, cytosolic beta-glucosidase Protein, glucosylceramidase beta 3 (gene/pseudogene) Protein, Gba3 Protein, gba3 Protein, GBA3 Protein, LOC100344458 Protein

Sujet:

Background: "Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to the glycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.

Synonym: CBG;CBGL1;GBA3;GLUC;KLrP;MGC104276;MGC126878

Poids moléculaire: 55 kDa

NCBI Accession: NP_066024