HDGF Protein (His tag)

N° du produit ABIN7318578

Détail du produit

Antigène: HDGF (Hepatoma-Derived Growth Factor (HDGF))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HDGF protéine est marqué à la His tag.

Fonction: Recombinant Human HDGF Protein (His Tag)

Séquence: Met 1-Tyr100

Attributs du produit: Recombinant Human Hepatoma-Derived Growth Factor is produced by our E.coli expression system and the target gene encoding Met1-Tyr100 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, 1 mM EDTA, pH 7.5.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: HDGF (Hepatoma-Derived Growth Factor (HDGF))

Autre désignation: HDGF (HDGF Produits)

Synonymes: HMG1L2 Protein, hmg1l2 Protein, HDGF Protein, DKFZp459H185 Protein, AI118077 Protein, D3Ertd299e Protein, heparin binding growth factor Protein, hepatoma-derived growth factor Protein, hepatoma-derived growth factor (high-mobility group protein 1-like) Protein, heparin binding growth factor L homeolog Protein, hepatoma-derived growth factor-like Protein, HDGF Protein, hdgf Protein, Hdgf Protein, hdgf.L Protein, LOC100357981 Protein

Sujet:

Background: Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.

Synonym: Hepatoma-Derived Growth Factor, HDGF, High Mobility Group Protein 1-Kike 2, HMG-1L2, HDGF, HMG1L2

Poids moléculaire: 12.6 kDa

UniProt: P51858

Pathways: ER-Nucleus Signaling