HMGB2 Protein (His tag)

N° du produit ABIN7318583

Détail du produit

Antigène: HMGB2 (High Mobility Group Box 2 (HMGB2))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette HMGB2 protéine est marqué à la His tag.

Fonction: Recombinant Human HMGB2 Protein (His Tag)

Séquence: Gly2-Glu209

Attributs du produit: Recombinant Human High Mobility Group Protein B2 is produced by our Mammalian expression system and the target gene encoding Gly2-Glu209 is expressed with a 6His tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: HMGB2 (High Mobility Group Box 2 (HMGB2))

Autre désignation: HMGB2 (HMGB2 Produits)

Synonymes: HMG2 Protein, C80539 Protein, HMG-2 Protein, Hmg2 Protein, HIGH MOBILITY GROUP BETA 1 Protein, HMG BETA 1 Protein, NFD02 Protein, NFD2 Protein, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02 Protein, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2 Protein, high mobility group B2 Protein, hmgb2 Protein, hmgb2l Protein, im:6909096 Protein, wu:fa20b02 Protein, zgc:101854 Protein, wu:fb22b10 Protein, wu:fc95d12 Protein, zgc:123215 Protein, high mobility group box 2 Protein, high mobility group box 2 S homeolog Protein, high mobility group B2 Protein, high mobility group box 2b Protein, high mobility group box 2a Protein, HMGB2 Protein, Hmgb2 Protein, hmgb2.S Protein, hmgb2b Protein, hmgb2a Protein

Sujet:

Background: High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Synonym: High Mobility Group Protein B2, High Mobility Group Protein 2, HMG-2, HMGB2, HMG2

Poids moléculaire: 25.1 kDa

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin