CD74 Protein (His tag)

N° du produit ABIN7320931

Détail du produit

Antigène: CD74 (HLA-DR-gamma (CD74))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CD74 protéine est marqué à la His tag.

Fonction: Recombinant Mouse CD74 protein (His Tag)

Séquence: 56Q-279L

Attributs du produit: A DNA sequence encoding theMouse CD74 protein (P04441) (56Q-279L) was expressed with a polyhistidine tag at the N-terminus.

Pureté: >90 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Immunogen(E-AB-40348)

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD74 (HLA-DR-gamma (CD74))

Autre désignation: CD74 (CD74 Produits)

Synonymes: DHLAG Protein, HLADG Protein, II Protein, Ia-GAMMA Protein, CLIP Protein, Ii Protein, INVG34 Protein, Iclp-1 Protein, iclp1 Protein, wu:fb11f09 Protein, wu:fb12a01 Protein, wu:fb13d06 Protein, wu:fk94e07 Protein, Iclp-2 Protein, cd74 Protein, iclp2 Protein, zgc:123161 Protein, CD74 molecule Protein, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Protein, CD74 molecule, major histocompatibility complex, class II invariant chain a Protein, CD74 molecule, major histocompatibility complex, class II invariant chain b Protein, CD74 Protein, Cd74 Protein, cd74a Protein, cd74b Protein

Sujet:

Background: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.

Synonym: CD 74,CD74,CD74 antigen (invariant polypeptide of major histocompatibility complex,class II antigen-associated),CD74 antigen,CD74 Molecule,CD74 Molecule,major histocompatibility complex,class II invariant chain,CLIP,DHLAG,Gamma chain of class II antigens,HG2A,HLA class II histocompatibility antigen gamma chain,HLA DR antigens associated invariant chain,HLA DR gamma,HLA-DR antigens-associated invariant chain,HLA-DR-gamma,HLADG,HLADR antigens associated invariant chain,Ia antigen associated invariant chain,Ia antigen-associated invariant chain,Ia associated invariant chain,Ia gamma,Ii,Invariant polypeptide of major histocompatibility complex class II antigen associated,la-gamma,Major histocompatibility complex class II invariant chain,MHC HLA DR gamma chain,MHC HLA-DR gamma chain,p33,p35,Protein 41

Poids moléculaire: 25.3kDa

UniProt: P04441

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints