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IL-2 Protein (His tag)

IL2 Origine: Rat Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7321270
  • Antigène Voir toutes IL-2 (IL2) Protéines
    IL-2 (IL2) (Interleukin 2 (IL2))
    Type de proteíne
    Recombinant
    Origine
    • 29
    • 17
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Source
    • 43
    • 25
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette IL-2 protéine est marqué à la His tag.
    Fonction
    Recombinant Rat Interleukin-2/IL-2 Protein (His Tag)
    Séquence
    Ala21-Gln155
    Attributs du produit
    Recombinant Rat Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Gln155 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 5 mM NaH2PO4, 5 mM Citric acid, 150 mM NaCl, pH 4.0.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    IL-2 (IL2) (Interleukin 2 (IL2))
    Autre désignation
    Interleukin-2/IL-2 (IL2 Produits)
    Synonymes
    IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
    Sujet

    Background: Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66 % and 73 % amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

    Synonym: Interleukin-2, IL-2, T-cell growth factor, TCGF, Aldesleukin, IL2

    Poids moléculaire
    16.3 kDa
    UniProt
    P17108
    Pathways
    Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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