IL20RB Protein (His tag)

N° du produit ABIN7321246

Détail du produit

Antigène: IL20RB (Interleukin 20 Receptor beta (IL20RB))

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: Cette IL20RB protéine est marqué à la His tag.

Fonction: Recombinant Rat IL20RB Protein (His Tag)

Séquence: Met1-Pro227

Attributs du produit: A DNA sequence encoding the rat IL20RB (B8K1X9) (Met1-Pro227) was expressed, fused with a polyhistidine tag at the C-terminus.

Pureté: > 91 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IL20RB (Interleukin 20 Receptor beta (IL20RB))

Autre désignation: IL20RB (IL20RB Produits)

Synonymes: DIRS1 Protein, FNDC6 Protein, IL-20R2 Protein, AV228068 Protein, Fndc6 Protein, Gm186 Protein, Il20R2 Protein, IL20R2 Protein, RGD1566151 Protein, interleukin 20 receptor subunit beta Protein, interleukin 20 receptor beta Protein, IL20RB Protein, Il20rb Protein

Sujet:

Background: IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons, cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.

Synonym: IL20RB

Poids moléculaire: 24.6 kDa

UniProt: B8K1X9

Pathways: Regulation of Leukocyte Mediated Immunity