IL20RB Protein (Fc Tag)

N° du produit ABIN7455661

Détail du produit

Antigène: IL20RB (Interleukin 20 Receptor beta (IL20RB))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL20RB protéine est marqué à la Fc Tag.

Fonction: Recombinant Human Interleukin-20 Receptor Subunit Beta/IL-20RB is produced by our Mammalian expression system and the target gene encoding Asp30-Ala230 is expressed with a Fc tag at the C-terminus.

Attributs du produit: Extracellular Domain Protein

Pureté: Greater than 85 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: -80 °C

Stockage commentaire: Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: IL20RB (Interleukin 20 Receptor beta (IL20RB))

Autre désignation: IL-20RB (IL20RB Produits)

Synonymes: DIRS1 Protein, FNDC6 Protein, IL-20R2 Protein, AV228068 Protein, Fndc6 Protein, Gm186 Protein, Il20R2 Protein, IL20R2 Protein, RGD1566151 Protein, interleukin 20 receptor subunit beta Protein, interleukin 20 receptor beta Protein, IL20RB Protein, Il20rb Protein

Sujet: Interleukin-20 receptor subunit beta, IL-20 receptor subunit beta, IL-20R-beta, IL-20RB, IL-20R2, DIRS1, hCG_2022374, FNDC6, MGC34923, fibronectin type III domain containing 6, interleukin-20 receptor IIInterleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons, cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

Poids moléculaire: 49.6 KDa

UniProt: Q6UXL0

Pathways: Regulation of Leukocyte Mediated Immunity