LAIR2 Protein (Fc Tag)

N° du produit ABIN7319838

Détail du produit

Antigène: LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette LAIR2 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human Leukocyte-associated Immunoglobulin-like Receptor 2/ LAIR2/CD306 (C-Fc)

Séquence: Gln22-Pro152

Attributs du produit: Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gln22-Pro152 is expressed with a Fc tag at the C-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))

Autre désignation: Leukocyte-associated Immunoglobulin-like Receptor 2/ LAIR2/CD306 (LAIR2 Produits)

Synonymes: CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein

Sujet:

Background: Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83 % amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.

Synonym: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2

Poids moléculaire: 41 kDa

UniProt: Q6ISS4