MARK3 Protein (GST tag,His tag)
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- Antigène Voir toutes MARK3 Protéines
- MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette MARK3 protéine est marqué à la GST tag,His tag.
- Fonction
- Recombinant Human MARK3/CTAK1/EMK-2 Protein (His & GST Tag)(Active)
- Séquence
- Met 1-Leu 729
- Attributs du produit
- A DNA sequence encoding full length of human MARK3 (AAH24773.1) (Met 1-Leu 729) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Pureté
- > 88 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 7 nmol/min/mg using synthetic CHKtide peptide (KKKVSRSGLYRSPSMPENLNRPR) as substrate.
- Top Product
- Discover our top product MARK3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 0.1 mM EDTA, pH 7.4, 10 % gly
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))
- Autre désignation
- MARK3/CTAK1/EMK-2 (MARK3 Produits)
- Synonymes
- MARK3 Protein, par1 Protein, par-1 Protein, Par-1A Protein, CTAK1 Protein, KP78 Protein, PAR1A Protein, Par-1a Protein, 1600015G02Rik Protein, A430080F22Rik Protein, C-TAK1 Protein, ETK-1 Protein, ETK1 Protein, Emk2 Protein, MPK10 Protein, fi39g08 Protein, wu:fi39g08 Protein, zgc:152848 Protein, zgc:55693 Protein, c-tak1 Protein, ctak1 Protein, emk-2 Protein, microtubule affinity regulating kinase 3 Protein, MAP/microtubule affinity-regulating kinase 3b Protein, MAP/microtubule affinity regulating kinase 3 Protein, MAP/microtubule affinity-regulating kinase 3a Protein, microtubule affinity regulating kinase 3 L homeolog Protein, MARK3 Protein, mark3b Protein, mark3 Protein, Mark3 Protein, mark3a Protein, mark3.L Protein
- Sujet
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Background: MAP / microtubule affinity-regulating kinase 3, also known as C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Serine/threonine-protein kinase p78, MARK3, CTAK1 and EMK2, is a ubiquitous expressed protein which belongs to the protein kinase superfamily, CAMK Ser / Thr protein kinase family and MARK subfamily. MARK3 contains one KA1 (kinase-associated) domain, one protein kinase domain and one UBA domain. The Par-1 / MARK protein kinases play a pivotal role in establishing cellular polarity. This family of kinases contains a unique domain architecture, in which a ubiquitin-associated (UBA) domain is located C-terminal to the kinase domain. MARKs / PAR-1 are common regulators of cell polarity that are conserved from nematode to human. All of these kinases have a highly conserved C-terminal domain, which is termed the kinase-associated domain 1 (KA1).
Synonym: CTAK1;KP78;Par-1a;PAR1A
- Poids moléculaire
- 109.3 kDa
- Pathways
- SARS-CoV-2 Protein Interactome
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