Moesin Protein (MSN) (AA 1-346) (His tag)

N° du produit ABIN7317213

Détail du produit

Antigène: Moesin (MSN)

Type de proteíne: Recombinant

Attributs du protein: AA 1-346

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Moesin protéine est marqué à la His tag.

Fonction: Recombinant Human MSN/Moesin Protein (aa 1-346, His Tag)

Séquence: Met 1-Glu 346

Attributs du produit: A DNA sequence encoding the human MSN (P26038) (Met 1-Glu 346) was expressed, with a polyhistidine tag at the N-terminus.

Pureté: > 80 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.5M NaCl, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Moesin (MSN)

Autre désignation: MSN/Moesin (MSN Produits)

Synonymes: CG10701 Protein, D17 Protein, Dmel\\CG10701 Protein, Dmoe Protein, EMR1 Protein, ERM Protein, Emr1 Protein, anon-WO03040301.155 Protein, anon-WO03040301.157 Protein, anon-WO03040301.159 Protein, anon-WO03040301.161 Protein, dMoe Protein, gma Protein, l(1)G0067 Protein, l(1)G0323 Protein, l(1)G0404 Protein, l(1)G0415 Protein, moe Protein, moesin/ezrin/radixin homolog mRNA Protein, cb567 Protein, rdx Protein, wu:fb14b03 Protein, zgc:85640 Protein, MSN Protein, C78546 Protein, moesin Protein, Moesin Protein, moesin a Protein, moesin L homeolog Protein, MSN Protein, Moe Protein, msna Protein, msn.L Protein, moes Protein, Msn Protein

Sujet:

Background: Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM proteins function as cross-linkers between plasma membranes and actin-based cytoskeletons. The sole Drosophila ERM protein, moesin, functions to promote cortical actin assembly and apical-basal polarity. As a result, cells lacking moesin lose epithelial characteristics and adopt invasive migratory behaviour. It is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. Moesin contains 1 FERM domain and is expressed in all tissues and cultured cells studied. Moesin has been shown to interact with CD43, Neutrophil cytosolic factor 1, VCAM-1, Neutrophil cytosolic factor 4, ICAM3 and EZR.

Synonym: HEL70

Poids moléculaire: 42.8 kDa

UniProt: P26038

Pathways: Asymmetric Protein Localization