NPX1 Protein (His tag)

N° du produit ABIN7319515

Détail du produit

Antigène: NPX1 (Neuronal Pentraxin 1 (NPX1))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette NPX1 protéine est marqué à la His tag.

Fonction: Recombinant Human NPTX1 Protein (His Tag)

Séquence: Gln23-Asn432

Attributs du produit: Recombinant Human NPTX1 is produced by our Mammalian expression system and the target gene encoding Gln23-Asn432 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS,1 mM EDTA,PH7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: NPX1 (Neuronal Pentraxin 1 (NPX1))

Autre désignation: NPTX1 (NPX1 Produits)

Synonymes: NP1 Protein, D11Bwg1004e Protein, Np1 Protein, np1 Protein, nptx1 Protein, neuronal pentraxin 1 Protein, neuronal pentraxin 1 L homeolog Protein, Nptx1 Protein, NPTX1 Protein, nptx1 Protein, nptx1.L Protein

Sujet:

Background: Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co-expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97 % aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it forms complexes with NPTXR. It may be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.

Synonym: Neuronal pentraxin-1,NPTX1,NP1

Poids moléculaire: 45.9 kDa

UniProt: Q15818

Pathways: Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome