PFKM Protein (GST tag,His tag)

N° du produit ABIN7197337

Détail du produit

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette PFKM protéine est marqué à la GST tag,His tag.

Fonction: Recombinant Human PFK1/PFKM Protein (His & GST Tag)

Séquence: Thr 2-Val 780

Attributs du produit: A DNA sequence encoding the human PFKM (P08237-1) (Thr2-Val780) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFK1/PFKM (PFKM Produits)

Synonymes: GSD7 Protein, PFK-1 Protein, PFK1 Protein, PFKA Protein, PFKX Protein, AI131669 Protein, PFK-A Protein, PFK-M Protein, Pfk-4 Protein, Pfk4 Protein, Pfka Protein, Pfkx Protein, Pfk-M Protein, M-PFK Protein, PFKM Protein, pfkm Protein, zgc:92344 Protein, pfk Protein, im:7137110 Protein, wu:fc58g11 Protein, phosphofructokinase, muscle Protein, phosphofructokinase, platelet Protein, phosphofructokinase, muscle a Protein, phosphofructokinase, muscle S homeolog Protein, phosphofructokinase, muscle b Protein, PFKM Protein, Pfkm Protein, PFKP Protein, pfkma Protein, pfkm.S Protein, pfkmb Protein

Sujet:

Background: PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations in PFK1 gene have been related with glycogen storage disease type VII, also identified as Tarui disease.

Synonym: 6-phosphofructokinase, muscle type,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphohexokinase,PFKM,PFKX,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PPP1R122

Poids moléculaire: 112.9 kDa

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg