PLTP Protein (His tag)

N° du produit ABIN7317633

Détail du produit

Antigène: PLTP (Phospholipid Transfer Protein (PLTP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PLTP protéine est marqué à la His tag.

Fonction: Recombinant Human PLTP Protein (His Tag)

Séquence: Met 1-Val 493

Attributs du produit: A DNA sequence encoding the human PLTP isoform 1 (P55058-1) (Met 1-Val 493) was expressed, fused with a polyhistidine tag at the C-terminus.

Pureté: > 80 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PLTP (Phospholipid Transfer Protein (PLTP))

Autre désignation: PLTP (PLTP Produits)

Synonymes: zgc:100903 Protein, MGC84445 Protein, PLTP Protein, hdlcq9 Protein, DKFZp469A1437 Protein, BPIFE Protein, HDLCQ9 Protein, Bpife Protein, OD107 Protein, phospholipid transfer protein Protein, phospholipid transfer protein S homeolog Protein, PLTP Protein, pltp Protein, pltp.S Protein, LOC542343 Protein, Pltp Protein

Sujet:

Background: Phospholipid transfer protein, also known as Lipid transfer protein II and PLTP, is a secreted protein which belongs to the BPI/LBP/Plunc superfamily and BPI / LBP family. PLTP is nearly ubiquitously expressed in cells and tissues. PLTP converts HDL into larger and smaller particles. It may play a key role in extracellular phospholipid transport and modulation of hdl particles. High-density lipoproteins (HDL) play a major protective role against the development of coronary artery disease. PLTP is a main factor regulating the size and composition of HDL in the circulation and plays an important role in controlling plasma HDL levels. This is achieved via both the phospholipid transfer activity of PLTP and its capability to cause HDL conversion. PLTP is one of the key lipid transfer proteins in plasma and cerebrospinal fluid. It is involved in novel intracellular functions. PLTP is an important modulator of lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL. PLTP also plays an important role in inflammation and oxidative stress. Accordingly, PLTP has also been implicated in the development of atherosclerosis.

Synonym: BPIFE;HDLCQ9

Poids moléculaire: 54.5 kDa

Pathways: Lipid Metabolism