PKD2 Protein (GST tag,His tag)
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- Antigène Voir toutes PKD2 Protéines
- PKD2 (Protein Kinase D2 (PKD2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette PKD2 protéine est marqué à la GST tag,His tag.
- Fonction
- Recombinant Human PRKD2/PKD2 Protein (His & GST Tag)(Active)
- Séquence
- Met 1-Leu 878
- Attributs du produit
- A DNA sequence encoding the amino acid sequence (Met 1-Leu 878) of human PRKD2 (NP_057541.2) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Pureté
- > 82 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be >30 nmol/min/mg using synthetic CREBtide peptide (KRREILSRRPSYR) as substrate.
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Protein Kinase D2 (PKD2) (AA 1-878) protein (GST tag)
PKD2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase D2 (PKD2) (AA 1-110) protein (GST tag)PKD2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase D2 (PKD2) (AA 1-878) protein (Strep Tag)Crystallography grade PKD2 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein Kinase D2 (PKD2) (AA 1-875) protein (Strep Tag)Crystallography grade PKD2 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein Kinase D2 (PKD2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PKD2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Kinase D2 (PKD2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PKD2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Kinase D2 (PKD2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PKD2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 50 mM Tris, 500 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 8.0
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- PKD2 (Protein Kinase D2 (PKD2))
- Autre désignation
- PRKD2/PKD2 (PKD2 Produits)
- Synonymes
- PKD2 Protein, nPKC-D2 Protein, AI325941 Protein, RGD1308054 Protein, PRKD2 Protein, protein kinase D2 Protein, serine/threonine-protein kinase D2 Protein, PRKD2 Protein, Prkd2 Protein, LOC100407181 Protein
- Sujet
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Background: Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein which belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-710 and phosphorylation of Ser-706 by PKC relieves auto-inhibition by the PH domain. PRKD2 / PKD2 converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
Synonym: HSPC187;nPKC-D2;PKD2
- Poids moléculaire
- 124 kDa
- NCBI Accession
- NP_057541
- Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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