REG4 Protein (His tag)
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- Antigène Voir toutes REG4 Protéines
- REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
- Type de proteíne
- Recombinant
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Origine
- Rat
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette REG4 protéine est marqué à la His tag.
- Fonction
- Recombinant Rat REG4 Protein (His Tag)
- Séquence
- Met1-Pro157
- Attributs du produit
- A DNA sequence encoding the rat REG4 (Q68AX7) (Met1-Pro157) was expressed, fused with a polyhistidine tag at the C-terminus.
- Pureté
- > 78 % as determined by SDS-PAGE
- niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product REG4 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
- Autre désignation
- REG4 (REG4 Produits)
- Synonymes
- GISP Protein, REG-IV Protein, RELP Protein, 2010002L15Rik Protein, regenerating family member 4 Protein, regenerating islet-derived family, member 4 Protein, Reg4 Protein, REG4 Protein
- Sujet
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Background: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
Synonym: REG4
- Poids moléculaire
- 17.3 kDa
- UniProt
- Q68AX7
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