SHMT1 Protein (His tag)
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- Antigène Voir toutes SHMT1 Protéines
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette SHMT1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human SHMT1 Protein (His Tag)
- Séquence
- Met3-Phe483
- Attributs du produit
- Recombinant Human Serine Hydroxymethyltransferase Cytosolic is produced by our Mammalian expression system and the target gene encoding Met3-Phe483 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SHMT1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- Autre désignation
- SHMT1 (SHMT1 Produits)
- Synonymes
- Shmt Protein, mShmt Protein, LRRGT00032 Protein, shmt1 Protein, MGC53442 Protein, zgc:66171 Protein, zgc:77524 Protein, SHMT1 Protein, Shmt1 Protein, CSHMT Protein, SHMT Protein, AI324848 Protein, AI385541 Protein, C81125 Protein, mshmt Protein, mshmt1 Protein, mshmt2 Protein, MEL-32 Protein, SHMT2 Protein, F20D10.50 Protein, F20D10_50 Protein, SERINE HYDROXYMETHYLTRANSFERASE 1 Protein, SERINE TRANSHYDROXYMETHYLASE Protein, SERINE TRANSHYDROXYMETHYLTRANSFERASE Protein, STM Protein, serine transhydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 (soluble) L homeolog Protein, serine hydroxymethyltransferase 1 (soluble) Protein, microRNA 6778 Protein, serine transhydroxymethyltransferase 1 Protein, Shmt1 Protein, shmt1.L Protein, shmt1 Protein, MIR6778 Protein, SHMT1 Protein, SHM1 Protein
- Sujet
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Background: Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.
Synonym: Serine Hydroxymethyltransferase Cytosolic, SHMT, Glycine Hydroxymethyltransferase, Serine Methylase, SHMT1
- Poids moléculaire
- 53.9 kDa
- UniProt
- P34896
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