SERPING1 Protein (His tag)

N° du produit ABIN7320645

Détail du produit

Antigène: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette SERPING1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse Serpin G1/C1IN Protein (His Tag)

Séquence: Ala20-Gly504

Attributs du produit: Recombinant Mouse Serine Protease Inhibitor-clade G1 is produced by our Mammalian expression system and the target gene encoding Ala20-Gly504 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Autre désignation: Serpin G1/C1IN (SERPING1 Produits)

Synonymes: fb64f02 Protein, im:7159527 Protein, si:dkeyp-110g5.2 Protein, wu:fb60c09 Protein, wu:fb62a08 Protein, wu:fb64f02 Protein, LOC100136072 Protein, C1-INH Protein, C1INH Protein, C1nh Protein, C1IN Protein, C1NH Protein, HAE1 Protein, HAE2 Protein, serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 Protein, C1 inhibitor Protein, serpin family G member 1 Protein, serine (or cysteine) peptidase inhibitor, clade G, member 1 Protein, serping1 Protein, LOC100136072 Protein, SERPING1 Protein, Serping1 Protein

Sujet:

Background: SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL. SERPIN G1 is a very efficient physiological inhibitor of FXIIa, plasma kallikrein and fXIa, and could inhibit chymotrypsin and kallikrein. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases in the C1 complex of classical pathway of complement. Activation of the C1 complex is under control of the C1-inhibitor.

Synonym: SERPIN G1,Plasma protease C1 inhibitor,C1 Inh,C1 esterase inhibitor,C1-inhibiting factor,Serping1,C1nh

Poids moléculaire: 54.6 kDa

UniProt: P97290

Pathways: Système du Complément