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SH2D1A Protein (His tag)

SH2D1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319330
  • Antigène Voir toutes SH2D1A Protéines
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SH2D1A protéine est marqué à la His tag.
    Fonction
    Recombinant Human SH2D1A/SAP Protein (His Tag)
    Séquence
    Met 1-Pro128
    Attributs du produit
    Recombinant Human SH2 Domain-Containing Protein 1A is produced by our E.coli expression system and the target gene encoding Met1-Pro128 is expressed with a 6His tag at the N-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SH2D1A Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 10 % Glycerol, pH 7.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    Autre désignation
    SH2D1A/SAP (SH2D1A Produits)
    Synonymes
    DSHP Protein, EBVS Protein, IMD5 Protein, LYP Protein, MTCP1 Protein, SAP Protein, SAP/SH2D1A Protein, XLP Protein, XLPD Protein, RGD1562408 Protein, Gm686 Protein, SH2D1A Protein, SH2 domain containing 1A Protein, SH2D1A Protein, Sh2d1a Protein
    Sujet

    Background: SH2 Domain-Containing Protein 1A,(SH2D1A) contains one SH2 domain and a short tail and is localized in the cytoplasm. SH2D1A is expressed at a high level in the thymus and the lung, with lower expression levels in the spleen and the liver. SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. In addition, SH2D1A mediates interaction between FYN and SLAMF1. It is also thought to regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.

    Synonym: SH2 Domain-Containing Protein 1A, Duncan Disease SH2-Protein, Signaling Lymphocytic Activation Molecule-Associated Protein, SLAM-Associated Protein, T-Cell Signal Transduction Molecule SAP, SH2D1A,DSHP,EBVS,IMD5,LYP,MTCP1,SAP/SH2D1A,XLP,XLPD,XLPD1

    Poids moléculaire
    16.3 kDa
    NCBI Accession
    NP_002342
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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