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SIAE Protein (His tag)

SIAE Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 97 % as determined by reducing SDS-PAGE.
N° du produit ABIN7198000
  • Antigène Voir toutes SIAE Protéines
    SIAE (Sialic Acid Acetylesterase (SIAE))
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 2
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification/Conjugué
    Cette SIAE protéine est marqué à la His tag.
    Fonction
    Recombinant Human SIAE Protein (Baculovirus, His Tag)
    Séquence
    Met 1-Lys523
    Attributs du produit
    A DNA sequence encoding the human SIAE (Met 1-Lys523) (Q9HAT2-1) was expressed, with a C-terminal polyhistidine tag.
    Pureté
    > 97 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SIAE Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    SIAE (Sialic Acid Acetylesterase (SIAE))
    Autre désignation
    SIAE (SIAE Produits)
    Synonymes
    MGC68688 Protein, MGC137441 Protein, zgc:56454 Protein, YSG2 Protein, DKFZp469J191 Protein, LSE Protein, Ysg2 Protein, RGD1310431 Protein, AIS6 Protein, CSE-C Protein, CSEC Protein, sialic acid acetylesterase L homeolog Protein, sialic acid acetylesterase Protein, siae.L Protein, SIAE Protein, siae Protein, Siae Protein
    Sujet

    Background: Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.

    Synonym: Sialate O-Acetylesterase, H-Lse, Sialic Acid-Specific 9-O-Acetylesterase, SIAE, YSG2,AIS6,CSE-C,CSEC

    Poids moléculaire
    57.4 kDa
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