SIAE Protein (His tag)
-
- Antigène Voir toutes SIAE Protéines
- SIAE (Sialic Acid Acetylesterase (SIAE))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Human Cells
- Purification/Conjugué
- Cette SIAE protéine est marqué à la His tag.
- Fonction
- Recombinant Human SIAE Protein (Human Cells, His Tag)
- Séquence
- Ile24-Lys523
- Attributs du produit
- Recombinant Human Sialate O-Acetylesterase is produced by our Mammalian expression system and the target gene encoding Ile24-Lys523 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SIAE Protéine
-
Sialic Acid Acetylesterase (SIAE) (AA 1-523) protein (GST tag)
SIAE Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Sialic Acid Acetylesterase (SIAE) (AA 24-275) protein (His tag)Crystallography grade SIAE Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Acetylesterase (SIAE) (AA 276-541) protein (His tag)Crystallography grade SIAE Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Acetylesterase (SIAE) (AA 24-523) protein (His tag)Crystallography grade SIAE Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Acetylesterase (SIAE) protein (Myc-DYKDDDDK Tag)SIAE Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Antigène
- SIAE (Sialic Acid Acetylesterase (SIAE))
- Autre désignation
- SIAE (SIAE Produits)
- Synonymes
- MGC68688 Protein, MGC137441 Protein, zgc:56454 Protein, YSG2 Protein, DKFZp469J191 Protein, LSE Protein, Ysg2 Protein, RGD1310431 Protein, AIS6 Protein, CSE-C Protein, CSEC Protein, sialic acid acetylesterase L homeolog Protein, sialic acid acetylesterase Protein, siae.L Protein, SIAE Protein, siae Protein, Siae Protein
- Sujet
-
Background: Sialate O-Acetylesterase (SIAE) belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. SIAE is widely expressed with high expression levels in the testis, prostate, and colon. SIAE catalyzes N-acetyl-O-acetylneuraminate and H2O to N-acetylneuraminate and acetate. SIAE removes O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. SIAE down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for immunological tolerance. Loss of function mutations in SIAE are much more frequently found in humans with autoimmune diseases especially rheumatoid arthritis and type 1 diabetes.
Synonym: Sialate O-Acetylesterase, H-Lse, Sialic Acid-Specific 9-O-Acetylesterase, SIAE, YSG2,AIS6,CSE-C,CSEC
- Poids moléculaire
- 57.0 kDa
- UniProt
- Q9HAT2
-
