TFAP2C Protein (His tag)

N° du produit ABIN7317304

Détail du produit

Antigène: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TFAP2C protéine est marqué à la His tag.

Fonction: Recombinant Human TFAP2C/AP2-GAMMA Protein (His Tag)

Séquence: Leu128-Val223

Attributs du produit: A DNA sequence encoding the mature form of human TFAP2C (Q92754) (Leu128-Val223) was expressed with a polyhistide tag at the N-terminus.

Pureté: > 98 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Autre désignation: TFAP2C/AP2-GAMMA (TFAP2C Produits)

Synonymes: erf1 Protein, hap-2g Protein, tfa2pc Protein, tfap2g Protein, ap2-gamma Protein, TFAP2C Protein, AP2-gamma Protein, Tcfap2c Protein, AP2-GAMMA Protein, ERF1 Protein, TFAP2G Protein, hAP-2g Protein, wu:fb48g05 Protein, wu:fb49c04 Protein, zgc:92088 Protein, ap-2g Protein, tfap2gamma Protein, AA409384 Protein, AP2gamma Protein, Ap-2.2 Protein, Stra2 Protein, transcription factor AP-2 gamma Protein, putative transcription factor ap-2 gamma Protein, transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) Protein, transcription factor AP-2 gamma S homeolog Protein, transcription factor AP-2, gamma Protein, tfap2c Protein, TFAP2C Protein, Smp_157840 Protein, Tfap2c Protein, tfap2c.S Protein

Sujet:

Background: TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested for association to diseases (Breast Neoplasms, Carcinoma) and proposed to participate in processes (cell-cell signaling, male gonad development, regulation of transcription from RNA polymerase II promoter). Proteins are expected to have molecular functions (DNA binding, protein binding, protein dimerization activity, transcription factor activity) and to localize in various compartments (membrane, nucleus).

Synonym: AP2-GAMMA,ERF1,hAP-2g,TFAP2G

Poids moléculaire: 12.3 kDa

UniProt: Q92754

Pathways: Stem Cell Maintenance