TGFBR3 Protein (His tag)

N° du produit ABIN7320903

Détail du produit

Antigène: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette TGFBR3 protéine est marqué à la His tag.

Fonction: Recombinant Mouse TGFBR3 (C-6His)

Séquence: Glu23-Thr785

Attributs du produit: Recombinant Mouse Transforming Growth Factor Beta Receptor Type 3 is produced by our Mammalian expression system and the target gene encoding Glu23-Thr785 is expressed with a 6His tag at the C-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Autre désignation: TGFBR3 (TGFBR3 Produits)

Synonymes: TGFBR3 Protein, DKFZp469I0915 Protein, BGCAN Protein, betaglycan Protein, 1110036H20Rik Protein, AU015626 Protein, AW215636 Protein, TBRIII Protein, transforming growth factor beta receptor 3 Protein, transforming growth factor, beta receptor III Protein, TGFBR3 Protein, tgfbr3 Protein, Tgfbr3 Protein

Sujet:

Background: Transforming growth factor beta receptor III (TGF-beta RIII, also betaglycan) is a ubiquitously expressed, 280 kDa type I transmembrane proteoglycan member of the TGF-beta superfamily of proteins. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. TGF-beta RIII can enhance or inhibit cell signaling. TGF-beta RIII has been shown to play an essential role in the formation of the atrioventricular cushion and coronary vessels during development of the heart. TGF beta RIII also plays a role in many cancers. Increased expression of TGF beta RIII is found in higher grade lymphomas, and reduced expression of TGF beta RIII is found with advanced stage neuroblastomas and ovarian carcinomas. Low TGF-beta RIII expression also correlates with higher grade among a cohort of breast cancers. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.

Synonym: InBGCAN, TBRIII, TGF-beta receptor type 3, TGF-beta receptor type III, TGF-beta RIII, TGFbetaRIII, TGFBR3, TGF-bRIII, TGFR-3, Transforming growth factor beta receptor III

Poids moléculaire: 85.9 kDa

UniProt: A0A0R4J097