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ULBP2 Protein (Fc Tag)

ULBP2 Origine: Humain Hôte: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7318835
  • Antigène Voir toutes ULBP2 Protéines
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    Humain
    Source
    • 7
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette ULBP2 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)(Active)
    Séquence
    Gly26-Ser217
    Attributs du produit
    Recombinant Human UL16 Binding Protein-2/NKG2D ligand 2 is produced by our Mammalian expression system and the target gene encoding Gly26-Ser217 is expressed with a Fc tag at the C-terminus.
    Pureté
    > 90 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human NKG2DL2-Fc at 8μg/ml(100 μl/well) can bind Human NKG2D-His(Cat: PKSH033409). The ED50 of Human NKG2DL2-Fc is 10.32 ug/ml .
    Top Product
    Discover our top product ULBP2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Autre désignation
    ULBP2/N2DL-2 (ULBP2 Produits)
    Synonymes
    N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
    Sujet

    Background: NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.

    Synonym: NKG2D Ligand 2, N2DL-2, NKG2DL2, ALCAN-Alpha, Retinoic Acid Early Transcript 1H, UL16-Binding Protein 2, ULBP2, N2DL2, RAET1H

    Poids moléculaire
    51.4 kDa
    UniProt
    Q9BZM5
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