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ULBP2 Protein (AA 26-216) (Fc Tag)

ULBP2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7454230
  • Antigène Voir toutes ULBP2 Protéines
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 26-216
    Origine
    Humain
    Source
    • 6
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette ULBP2 protéine est marqué à la Fc Tag.
    Fonction
    Human ULBP-2 Protein
    Séquence
    Gly26-Ser216
    Attributs du produit
    Recombinant Human ULBP-2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly26-Ser216.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human NKG2D, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human ULBP-2, hFc Tag with the EC50 of 94.7ng/ml determined by ELISA. See testing image for detail.
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    Discover our top product ULBP2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Autre désignation
    ULBP-2 (ULBP2 Produits)
    Synonymes
    N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
    Sujet
    ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
    Poids moléculaire
    48.40 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9BZM5
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