VSTM1 Protein (His tag)

N° du produit ABIN7319179

Détail du produit

Antigène: VSTM1 (V-Set and Transmembrane Domain Containing 1 (VSTM1))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette VSTM1 protéine est marqué à la His tag.

Fonction: Recombinant Human VSTM1 Protein (His Tag)

Séquence: Tyr17-Thr135

Attributs du produit: Recombinant Human V-set and Transmembrane Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr17-Thr135 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: VSTM1 (V-Set and Transmembrane Domain Containing 1 (VSTM1))

Autre désignation: VSTM1 (VSTM1 Produits)

Synonymes: SIRL1 Protein, UNQ3033 Protein, V-set and transmembrane domain containing 1 Protein, VSTM1 Protein

Sujet:

Background: V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.

Synonym: V-set and transmembrane domain-containing protein 1,SIRL-1,Signal inhibitory receptor on leukocytes-1,VSTM1

Poids moléculaire: 14.6 kDa

UniProt: Q6UX27