ZIKV E Protein (His tag)

N° du produit ABIN7198747

Détail du produit

Antigène: ZIKV E (Zika Virus Envelope (ZIKV E))

Type de proteíne: Recombinant

Origine: Zika Virus (ZIKV)

Source: Levure

Purification/Conjugué: Cette ZIKV E protéine est marqué à la His tag.

Fonction: Recombinant ZIKV E / Envelope protein (Domain III, His Tag)

Séquence: Val593-Lys699

Attributs du produit: A DNA sequence encoding the Zika virus (strain Zika SPH2015) E / Envelope (domain III) (ALU33341.1) (Val593-Lys699) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE.

niveau d'endotoxine: Please contact us for more information.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ZIKV E (Zika Virus Envelope (ZIKV E))

Autre désignation: Zika Envelope (ZIKV E Produits)

Sujet:

Background: Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76 % of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.

Synonym: Zika virus, E protein, strain Zika SPH2015

Poids moléculaire: 13kDa.