TNNC1 Protein (His tag)

N° du produit ABIN7319455

Détail du produit

Antigène: TNNC1 (Cardiac Troponin C (TNNC1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TNNC1 protéine est marqué à la His tag.

Fonction: Recombinant Human Troponin C/TNNC1 Protein (His Tag)

Séquence: Met1-Glu161

Attributs du produit: Recombinant Human Troponin C is produced by our E.coli expression system and the target gene encoding Met1-Glu161 is expressed with a 6His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Commentaires:

17-20 kDa

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT,10 % glycerol, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: TNNC1 (Cardiac Troponin C (TNNC1))

Autre désignation: TNNC1 (TNNC1 Produits)

Synonymes: CMD1Z Protein, CMH13 Protein, TN-C Protein, TNC Protein, TNNC Protein, cTnC Protein, tnnc1 Protein, zgc:103465 Protein, PCTNC1 Protein, cmd1z Protein, cmh13 Protein, tnc Protein, tnnc Protein, MGC80066 Protein, TNNC1 Protein, AI874626 Protein, TnC Protein, cTnI Protein, tncc Protein, Tncc Protein, stnnc Protein, zgc:86932 Protein, troponin C1, slow skeletal and cardiac type Protein, troponin C type 1a (slow) Protein, troponin C type 1 (slow) L homeolog Protein, cardiac troponin C Protein, troponin C, cardiac/slow skeletal Protein, troponin C type 1b (slow) Protein, TNNC1 Protein, tnnc1a Protein, tnnc1.L Protein, tnnc1 Protein, Tnnc1 Protein, tnnc1b Protein

Sujet:

Background: Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2(encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93 % amino acid sequence identity with mouse and rat cardiac Troponin I.

Synonym: CMD1Z,CMH13,TN-C,TNC,TNNC

Poids moléculaire: 19.8 kDa

UniProt: P63316