FGL1 Protein (His tag,Biotin)

N° du produit ABIN7319771

Détail du produit

Antigène: FGL1 (Fibrinogen-Like 1 (FGL1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette FGL1 protéine est marqué à la His tag,Biotin.

Fonction: Recombinant Human FGL1 (C-Avi-6His) Biotinylated

Séquence: Leu23-Ile312

Attributs du produit: Biotinylated Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a Avi, 6His tag at the C-terminus.

Pureté: >90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human LAG-3-Fc(Cat#CU30) at 10μg/ml (100 μl/well) can bind  Biotinylated Human FGL1-Avi(Cat#CY21). The ED50 of Human FGL1-Avi (Cat#CY21) is 1908ng/mL.

Information d'application

Commentaires:

35 kDa

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 10 % Glycerol, 2 mM EDTA, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: FGL1 (Fibrinogen-Like 1 (FGL1))

Autre désignation: FGL1 (FGL1 Produits)

Synonymes: MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein

Sujet:

Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

Synonym: Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1

Poids moléculaire: 36.6 kDa

UniProt: Q08830