HLA DQA1*01:01-DQB1*06:02 protein (V5 tag,SBP Tag,His tag)
Origine: Humain
Hôte: Mammalian Cells
Recombinant
> 80 %
BP, CP, ELISA, Neut
-
- Antigène
- HLA DQA1*01:01-DQB1*06:02
- Type de proteíne
- Recombinant
- Origine
- Humain
- Source
- Mammalian Cells
- Purification/Conjugué
- V5 tag,SBP Tag,His tag
- Application
- Blocking Peptide (BP), Control Peptide (CP), ELISA, Neutralization (Neut)
- Fonction
- The product is HLA DQA1*01:01-DQB1*06:02 as zipper-stabilized heterodimer
- Séquence
-
alpha chain: EDIVADHVAS YGVNLYQSYG PSGQFTHEFD GDEEFYVDLE RKETVWKLPL FHRLRFDPQF ALTNIAVLKH NLNILIKRSN STAATNEVPE VTVFSKSPVT LGQPNTLICL VDNIFPPVVN ITWLSNGHSV TEGVSETSFL SKSDHSFFKI SYLTFLPSAD EIYDCKVEHW GLDEPLLKHW EPEIPAPMSE LTET
beta chain: RDSPEDFVFQ FKGMCYFTNG TERVRLVTRY IYNREEYARF DSDVGVYRAV TPQGRPDAEY WNSQKEVLEG TRAELDTVCR HNYEVAFRGI LQRRVEPTVT ISPSRTEALN HHNLLVCSVT DFYPGQIKVR WFRNDQEETA GVVSTPLIRN GDWTFQILVM LEMTPQRGDV YTCHVEHPSL QSPITVEWRA QSESAQSK
Sequences without tags. Tag location is at the discretion of the manufacturer. - Specificité
- HLA DQA1*01:01-DQB1*06:02, P01909 / P01920
- Attributs du produit
- HLAs are produced in mammalian cell cultures as recombinant, truncated, soluble antigens, as zipper-stabilized heterodimers (HLA class II). As part of our quality control, all HLA are analyzed for purity by gel electrophoresis, concentration is determined by ELISA (0.5 mg/ml) and their functionality is verified with a specific antiserum.
- Purification
- Chromatography
- Pureté
- > 80 %
- niveau d'endotoxine
- Endotoxins have not been removed
-
- Indications d'application
- ELISA: 10 - 1000 ng/mL
- Commentaires
-
sandwich ELISA, direct ELISA, bead ELISA, reactive with antibodies anti-V5 and anti-His and specific antiserum, B cell ELI Spot (predicted), in vitro memory B cell stimulation (predicted), HLA competition assay (predicted), control in various assays (predicted)
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate based buffer, pH 7.8, Sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 6 months
-
- Antigène
- HLA DQA1*01:01-DQB1*06:02
- Sujet
- Human Leukozyte Antigen, human Antigen-presenting major histocompatibility complex class II (MHCII) molecule. Expressed on Antigen-presenting cells (APC), displays peptides to CD4-positive T cells. Involved in cellular immune response.
- Poids moléculaire
- approx. 60 - 65 kDa (approx. 29 kDa alpha chain and 34 - 38 kDa beta chain)
- UniProt
- P01909
-
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