2B4 Protein (AA 22-221) (Fc Tag)
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- Antigène Voir toutes 2B4 (CD244) Protéines
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-221
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette 2B4 protéine est marqué à la Fc Tag.
- Fonction
- Human 2B4/CD244/SLAMF4 Protein
- Séquence
- Cys22-Arg221
- Attributs du produit
- Recombinant Human 2B4/CD244/SLAMF4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Cys22-Arg221.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CD48, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 0.45μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CD244 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- Autre désignation
- 2B4 (CD244 Produits)
- Synonymes
- CD244 Protein, 2B4 Protein, NAIL Protein, NKR2B4 Protein, Nmrk Protein, SLAMF4 Protein, C9.1 Protein, F730046O15Rik Protein, Ly90 Protein, CD244 molecule Protein, CD244 natural killer cell receptor 2B4 Protein, CD244 Protein, Cd244 Protein
- Sujet
- 2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness.
- Poids moléculaire
- 49 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.
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