Amphiregulin Protein (AREG) (AA 101-187) (Fc Tag)
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- Antigène Voir toutes Amphiregulin (AREG) Protéines
- Amphiregulin (AREG)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 101-187
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Amphiregulin protéine est marqué à la Fc Tag.
- Fonction
- Human AREG Protein
- Séquence
- Ser101-Lys187
- Attributs du produit
- Recombinant Human AREG Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser101-Lys187.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human AREG, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-AREG Antibody, hFc Tag with the EC50 of 21.5ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product AREG Protéine
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Amphiregulin (AREG) (Active) protein
AREG Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 100-248) protein (Fc Tag)AREG Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Amphiregulin (AREG) (AA 101-198) protein (His-IF2DI Tag)AREG Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 20-129) protein (GST tag)AREG Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 101-187) protein (rho-1D4 tag)Crystallography grade AREG Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amphiregulin (AREG) (AA 100-248) protein (rho-1D4 tag)Crystallography grade AREG Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Amphiregulin (AREG)
- Autre désignation
- AREG (AREG Produits)
- Synonymes
- AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
- Sujet
- Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF-κB signalling pathway in pancreatic cancer cells.
- Poids moléculaire
- 37.3 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
- UniProt
- P15514
- Pathways
- Signalisation RTK, EGFR Signaling Pathway
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