CHIA Protein (AA 22-476) (His tag)

N° du produit ABIN7273824

Détail du produit

Antigène: CHIA (Chitinase, Acidic (CHIA))

Type de proteíne: Recombinant

Attributs du protein: AA 22-476

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CHIA protéine est marqué à la His tag.

Fonction: Human AMCase/CHIA Protein

Séquence: Tyr22-Ala476

Attributs du produit: Recombinant Human AMCase/CHIA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr22-Ala476.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CHIA (Chitinase, Acidic (CHIA))

Autre désignation: AMCase (CHIA Produits)

Synonymes: chia-a Protein, AMCASE Protein, CHIT2 Protein, TSA1902 Protein, 2200003E03Rik Protein, AMCase Protein, YNL Protein, CHIA Protein, chioIIa Protein, fa55g10 Protein, wu:fa55g10 Protein, zgc:63792 Protein, acidic mammalian chitinase Protein, chitinase, acidic Protein, chitinase, acidic S homeolog Protein, chitinase-M31, acidic Protein, chitinase, acidic 1 Protein, chitinase, acidic.4 Protein, LOC703284 Protein, CHIA Protein, LOC100600050 Protein, chia.S Protein, CHIA-M31 Protein, Chia1 Protein, Chia Protein, chia.4 Protein

Sujet: Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages' full maturation and polarization.

Poids moléculaire: 51.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.