CHIA Protein (AA 22-473) (His tag)

N° du produit ABIN7273825

Détail du produit

Antigène: CHIA (Chitinase, Acidic (CHIA))

Type de proteíne: Recombinant

Attributs du protein: AA 22-473

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette CHIA protéine est marqué à la His tag.

Fonction: Mouse AMCase/CHIA Protein

Séquence: Tyr22-Pro473

Attributs du produit: Recombinant Mouse AMCase/CHIA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr22-Pro473.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CHIA (Chitinase, Acidic (CHIA))

Autre désignation: AMCase (CHIA Produits)

Synonymes: chia-a Protein, AMCASE Protein, CHIT2 Protein, TSA1902 Protein, 2200003E03Rik Protein, AMCase Protein, YNL Protein, CHIA Protein, chioIIa Protein, fa55g10 Protein, wu:fa55g10 Protein, zgc:63792 Protein, acidic mammalian chitinase Protein, chitinase, acidic Protein, chitinase, acidic S homeolog Protein, chitinase-M31, acidic Protein, chitinase, acidic 1 Protein, chitinase, acidic.4 Protein, LOC703284 Protein, CHIA Protein, LOC100600050 Protein, chia.S Protein, CHIA-M31 Protein, Chia1 Protein, Chia Protein, chia.4 Protein

Sujet: Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. The expression of AMCase and CHIT-1 were differently modulated in HMMs at different stage of maturation.

Poids moléculaire: 51 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.

UniProt: Q91XA9