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APOE Protein (AA 19-311) (His tag)

APOE Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7273869
  • Antigène Voir toutes APOE Protéines
    APOE (Apolipoprotein E (APOE))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-311
    Origine
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 15
    • 14
    • 9
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette APOE protéine est marqué à la His tag.
    Fonction
    Mouse APOE/Apolipoprotein E Protein
    Séquence
    Glu19-Gln311
    Attributs du produit
    Recombinant Mouse APOE/Apolipoprotein E Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu19-Gln311.
    Pureté
    > 95 % as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 5.08 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product APOE Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    APOE (Apolipoprotein E (APOE))
    Autre désignation
    APOE (APOE Produits)
    Synonymes
    ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
    Sujet
    Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
    Poids moléculaire
    35.1 kDa same as Tris-Bis PAGE result.
    UniProt
    P08226
    Pathways
    Regulation of Cell Size, Lipid Metabolism
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