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BTLA Protein (AA 30-176) (His tag)

BTLA Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274000
  • Antigène Voir toutes BTLA Protéines
    BTLA (B and T Lymphocyte Associated (BTLA))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 30-176
    Origine
    • 33
    • 11
    • 2
    • 1
    Souris
    Source
    • 28
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette BTLA protéine est marqué à la His tag.
    Fonction
    Mouse BTLA Protein
    Séquence
    Glu30-Gly176
    Attributs du produit
    Recombinant Mouse BTLA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu30-Gly176.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product BTLA Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BTLA (B and T Lymphocyte Associated (BTLA))
    Autre désignation
    BTLA (BTLA Produits)
    Synonymes
    BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
    Sujet
    B- and T-lymphocyte attenuator (BTLA, CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.
    Poids moléculaire
    17.8 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.
    UniProt
    Q32MV9
    Pathways
    Cancer Immune Checkpoints
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