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PTK7 Protein (AA 31-704) (His tag)

PTK7 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274040
  • Antigène Voir toutes PTK7 Protéines
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 31-704
    Origine
    • 14
    • 6
    • 3
    • 2
    • 1
    • 1
    Humain
    Source
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PTK7 protéine est marqué à la His tag.
    Fonction
    Human PTK7/CCK4 Protein
    Séquence
    Ala31-Thr704
    Attributs du produit
    Recombinant Human PTK7/CCK4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala31-Thr704.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    Autre désignation
    PTK7 (PTK7 Produits)
    Synonymes
    PTK7 Protein, CCK-4 Protein, CCK4 Protein, Srf Protein, 8430404F20Rik Protein, chz Protein, mPTK7/CCK4 Protein, KLG Protein, protein tyrosine kinase 7 (inactive) Protein, protein tyrosine kinase 7 Protein, PTK7 protein tyrosine kinase 7 Protein, PTK7 Protein, Ptk7 Protein
    Sujet
    Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.
    Poids moléculaire
    75.7 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.
    Pathways
    Signalisation RTK, Tube Formation
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