IL2RG Protein (AA 23-254) (Fc Tag)
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- Antigène Voir toutes IL2RG Protéines
- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-254
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL2RG protéine est marqué à la Fc Tag.
- Fonction
- Human IL-2 R gamma/CD132 Protein
- Séquence
- Leu23-Asn254
- Attributs du produit
- Recombinant Human IL-2 R gamma/CD132 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Asn254.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 28.93 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
- Autre désignation
- IL-2 R gamma (IL2RG Produits)
- Synonymes
- Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein
- Sujet
- The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.
- Poids moléculaire
- 54.14 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result.
- Pathways
- Signalistation JAK/STAT, Growth Factor Binding
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