CD3D & CD3E (AA 23-108) protein (Fc Tag)
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- Antigène
- CD3D & CD3E
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-108
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Fc Tag
- Fonction
- Mouse CD3E & CD3D/CD3 epsilon & CD3 delta Protein
- Séquence
- Asp23-Asp108 (CD3E) & Phe22-Ala105 (CD3D)
- Specificité
- Uni-Prot: P22646 (CD3E), P04235 (CD3D)
- Attributs du produit
- Recombinant Mouse CD3E & CD3D/CD3 epsilon & CD3 delta Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp23-Asp108(CD3E) & Phe22-Ala105(CD3D).
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CD3D & CD3E
- Autre désignation
- CD3E&CD3D
- Synonymes
- AI504783 Protein, CD3 Protein, CD3epsilon Protein, T3e Protein, CD3 antigen, epsilon polypeptide Protein, Cd3e Protein
- Sujet
- T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
- Poids moléculaire
- 36.1 kDa (CD3E) and 35.2 kDa (CD3D). Due to glycosylation,the protein migrates to 50-65 kDa and 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- P22646
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