CADM3 Protein (AA 25-329) (His tag)

N° du produit ABIN7274328

Détail du produit

Antigène: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Type de proteíne: Recombinant

Attributs du protein: AA 25-329

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CADM3 protéine est marqué à la His tag.

Fonction: Human CADM3 Protein

Séquence: Asn25-Tyr329

Attributs du produit: Recombinant Human CADM3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn25-Tyr329.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Autre désignation: CADM3 (CADM3 Produits)

Synonymes: BIgR Protein, IGSF4B Protein, NECL1 Protein, Necl-1 Protein, TSLL1 Protein, synCAM3 Protein, Igsf4b Protein, Necl1 Protein, SynCAM3 Protein, Tsll1 Protein, necl1 Protein, cell adhesion molecule 3 Protein, cell adhesion molecule 3 S homeolog Protein, CADM3 Protein, Cadm3 Protein, cadm3.S Protein

Sujet: Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compared to DRG neurons.

Poids moléculaire: 34.6 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.

Pathways: Cell-Cell Junction Organization