CLEC12A Protein (AA 32-232) (His tag)
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- Antigène Voir toutes CLEC12A Protéines
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 32-232
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Origine
- Cynomolgus
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CLEC12A protéine est marqué à la His tag.
- Fonction
- Cynomolgus CLEC12A/MICL/CLL-1 Protein
- Séquence
- His32-Ala232
- Attributs du produit
- Recombinant Cynomolgus CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His32-Ala232.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Anti-CLEC12A Antibody captured on CM5 Chip via Protein A can bind Cynomolgus CLEC12A, His Tag with an affinity constant of 1.28 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product CLEC12A Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
- Autre désignation
- CLEC12A (CLEC12A Produits)
- Synonymes
- MGC179455 Protein, CLL-1 Protein, CLL1 Protein, DCAL-2 Protein, MICL Protein, D230024O04 Protein, KLRL1 Protein, Micl Protein, C-type lectin domain family 12 member A Protein, C-type lectin domain family 12, member a Protein, C-type lectin domain family 12, member A Protein, CLEC12A Protein, Clec12a Protein
- Sujet
- CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.
- Poids moléculaire
- 24.6 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WXQ6
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