+49 (0)241 95 163 153
+49 (0)241 95 163 155

CLEC12A Protein (AA 65-265) (AVI tag,Fc Tag,Biotin)

CLEC12A Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN6973030
  • Antigène Voir toutes CLEC12A Protéines
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Type de proteíne
    Activité biologique
    Attributs du protein
    AA 65-265
    • 15
    • 3
    • 1
    • 1
    • 14
    • 2
    • 2
    • 2
    HEK-293 Cells
    Cette CLEC12A protéine est marqué à la AVI tag,Fc Tag,Biotin.
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    Attributs du produit
    Biotinylated Human CLEC12A / MICL / CLL-1 Protein, Fc,Avitag™
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CLEC12A Protéine
  • Commentaires

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    For Research Use only
  • Format
    PBS, pH 7.4
    -20 °C
  • Antigène
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Autre désignation
    CLEC12A (CLEC12A Produits)
    MGC179455 Protein, CLL-1 Protein, CLL1 Protein, DCAL-2 Protein, MICL Protein, D230024O04 Protein, KLRL1 Protein, Micl Protein, C-type lectin domain family 12 member A Protein, C-type lectin domain family 12, member a Protein, C-type lectin domain family 12, member A Protein, CLEC12A Protein, Clec12a Protein
    CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
    Poids moléculaire
    51.9 kDa
    NCBI Accession
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