SARS-CoV-2 Spike S1 Protein (Deltacron) (His tag)
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- Antigène Voir toutes SARS-CoV-2 Spike S1 Protéines
- SARS-CoV-2 Spike S1
- Type de proteíne
- Recombinant
- Attributs du protein
- Deltacron
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Origine
- SARS Coronavirus-2 (SARS-CoV-2)
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SARS-CoV-2 Spike S1 protéine est marqué à la His tag.
- Fonction
- SARS-COV-2 Spike S1 (Deltacron) Protein
- Séquence
- Gln14-Arg683 (T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H)
- Attributs du produit
- Recombinant SARS-COV-2 Spike S1(Deltacron) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln14-Arg683(T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H). Alanine substitutions (R683A) are introduced to stabilize the trimeric prefusion state of SARS-COV-2 Spike S1(Deltacron) Protein and abolish the furin cleavage site, respectively.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized SARS-COV-2 Spike S1 (Deltacron) , His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human ACE2, hFc Tag with the EC50 of 65.9ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product SARS-CoV-2 Spike S1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Stock
- -80 °C
- Stockage commentaire
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SARS-CoV-2 Spike S1
- Abstract
- SARS-CoV-2 Spike S1 Produits
- Synonymes
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Classe de substances
- Viral Protein
- Sujet
- The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Poids moléculaire
- 73.94 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.
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